甲氧苄啶/Trimethoprim
編輯歷史
| 時間 | 作者 | 版本 |
|---|---|---|
| 2017-07-12 04:30 – 05:08 | r0 – r2 | |
顯示 diff+ 甲氧苄啶/Trimethoprim
+
+ Trimethoprim (TMP) is an antibiotic(抗细菌药) used mainly in the treatment of urinary tract infections(泌尿道感染).[1] Other uses include for middle ear infections(中耳炎) and travelers' diarrhea. With sulfamethoxazole(複方新諾明) or dapsone(達普頌) it may be used for pneumocystis carinii pneumonia(肺囊蟲肺炎) in people with HIV/AIDS(艾滋病). It is taken by mouth.[1]
+
+
+
+ Common side effects include nausea, changes in taste, and rash. Rarely it may result in blood problems such as not enough platelets(血小板) or white blood cells(白血球). May cause sun sensitivity.[1] There is evidence of potential harm during pregnancy(妊娠) in some animals but not humans.[2] It works by blocks folate(叶酸) metabolism in some bacteria which results in their death.[1]
+
+
+ Trimethoprim was first used in 1962.[3] It is on the World Health Organization's List of Essential Medicines(世界卫生组织基本药物标准清单), the most important medications needed in a basichealth system.[4] It is available as a generic medication and is not very expensive.[5] In the United States 10 days of treatment is about 21 USD.[1]
+
+ *^ 移至：a b c d e "Trimethoprim". The American Society of Health-System Pharmacists. Retrieved Aug 1, 2015.
+ *移至^ "Prescribing medicines in pregnancy database". Australian Government. 3 March 2014. Retrieved 22 April 2014.
+ *移至^ Huovinen, P (1 June 2001). "Resistance to trimethoprim-sulfamethoxazole.". Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 32(11): 1608–14. PMID(PubMed) 11340533.
+ *移至^ "WHO Model List of EssentialMedicines" (PDF). World Health Organization. October 2013. Retrieved 22 April 2014.
+ *移至^ Hamilton, Richart (2015). Tarascon Pocket Pharmacopoeia 2015 Deluxe Lab-Coat Edition. Jones & Bartlett Learning. p. 113. ISBN(国际标准书号) 9781284057560.
+ *
|
||