https://en.wikipedia.org/wiki/Wikipedia:WikiProject_Medicine/Translation_task_force/RTT/Simple_dapsone
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Dapsone, also known as diaminodiphenyl sulfone (DDS),[1] is an antibiotic commonly used in combination with rifampicin and clofaziminefor the treatment of leprosy.[2] It is a second-line medication for the treatment and prevention ofPneumocystis pneumonia and for the prevention of toxoplasmosis in those who have poor immune function.[2] Additionally it has been used for acne as well as other skin conditions.[3]Dapsone is available both topically and by mouth.[4]
’’’達普頌’’’（{{lang-en|Dapsone}}）又稱’’’氨苯碸’’’、’’’二胺苯碸’’’或’’’DDS’’’（diaminodiphenyl sulfone） [1]，是一種[[[抗生素]]，常與[[利福平]]和{{le|氯苯吩嗪|Clofazimine}}一起使用並用於治療[[痲瘋病]] [2]。達普頌是治療[[肺囊蟲肺炎]]的第二線藥物，也是[[免疫缺陷]]者預防[[弓蟲症]]的藥物 [2]。它也可以用來治療[[粉刺]]等皮膚問題 [3]。達普頌可以口服也可以是局部外用藥 [4]。
Severe side effects may include: a decrease in blood cells, red blood cell breakdown especially in those with glucose-6-phosphate dehydrogenase deficiency (G-6-PD), or hypersensitivity.[2] Common side effects include nausea and loss of appetite.[4] Other side effects include liver inflammation and a number of types of skin rashes.[2] While it is not entirely clear the safety of use during pregnancy some physicians recommend that it be continued in those with leprosy.[2] It is of the sulfoneclass.[2]
常見的副作用有[[噁心]]和缺乏[[食慾]]；嚴重的副作用包括{{le|顆粒性白血球缺乏症|Agranulocytosis}}、[[溶血反應]]（尤其是[[蠶豆症]]患者）和[[超敏反應]] [2]。而其他的副作用則包含了[[肝炎]]和[[皮疹]] [2]。雖然對於孕婦的安全性還不是完全清楚，但有些醫生還是持續讓痲瘋病的孕婦使用達普頌 [2]。達普頌屬於[[砜]]類[[2]]。
Dapsone was first studied as an antibiotic in 1937.[3] Its use for leprosy began in 1945.[3] It is on the World Health Organization’s List of Essential Medicines, the most important medications needed in a basic health system.[5]The oral form is available as a generic drug and not very expensive.[2][6]
達普頌於1908年被合成出來，自1937年開始研究其抗生素機制，1945年開始被使用於治療痲瘋病 [3]。達普頌被[[世界衛生組織]]列在[[世界衛生組織基本藥物標準清單|基本藥物清單]]中，是各醫療體系中重要的藥物 [5]。口服的達普頌屬於價格不高的[[學名藥]] [2][6]。
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