苯丙氨基戊烷(PPAP)

其實呢...那個中文名稱是google翻譯出來的XD大家幫忙取名吧XDD

英文條目:https://en.wikipedia.org/wiki/Phenylpropylaminopentane

中文條目:https://zh.wikipedia.org/wiki/%E8%8B%AF%E4%B8%99%E6%B0%A8%E5%9F%BA%E6%88%8A%E7%83%B7

Phenylpropylaminopentane

(-)-1-Phenyl-2-propylaminopentane (also known as (-)-PPAP and N,α-dipropylphenethylamine)[1][2][3] is a stimulant of the phenethylamine and amphetamine classes with an unusual effects profile and mechanism of action.[4]

’’’1-苯基-2-丙基氨基戊烷’’’(又稱為’’’N,α-二丙基苯乙胺’’’,簡稱’’’PPAP’’’)<ref>{{cite web | url=http://www.google.de/patents/US5220068 | title=Patent US 5220068 - Psychostimulant agent | date=15 June 1993 | author=Jozsef Knoll}}</ref><ref>{{cite web | url=http://www.google.de/patents/US6214859 | title=Patent US 6214859 - Ethylamine derivatives | date=10 April 2001 | author=Fumio Yoneda}}</ref><ref>{{cite web | url=http://www.google.de/patents/US5075338 | title=Patent US 5075338 - Method of treatment of learning deficiency | date=24 December 2001 | author=Jozsef Knoll}}</ref>,是[[苯乙胺]]及[[安非他命]]類的[[興奮劑]],具有特殊的作用機制及效果<ref>{{cite journal | url=http://www.ncbi.nlm.nih.gov/pubmed/1356324 | title=The pharmacology of 1-phenyl-2-propylamino-pentane (PPAP), a deprenyl-derived new spectrum psychostimulant. |vauthors=Knoll J, Knoll B, Török Z, Timár J, Yasar S | journal=Archives internationales de Pharmacodynamie et de Thérapie | date=March–April 1992 | issue=316 | pages=5–29 | pmid=1356324}}</ref>。

(-)-PPAP is classified as a monoaminergic activity enhancer that stimulates the impulse propagation mediated transmitter release of the neurotransmitters dopamine, norepinephrine and serotonin in the brain. 

苯丙氨基戊烷屬於[[單胺類神經遞質]]活動的増效劑。此類増效劑可刺激腦中衝動介導的遞質釋放([[多巴胺]]、[[腎上腺素]]、[[血清素]])。

Unlike stimulants such as amphetamine, which release a flood of monoamine neurotransmitters in an uncontrolled manner, (-)-PPAP instead only increases the amount of neurotransmitters that get released when a neuron is stimulated by receiving an impulse from a neighbouring neuron.

安非他命這類興奮劑會促進大量神經遞質釋出。苯丙氨基戊烷只有在[[神經元]]受鄰近神經元刺激時才會增加神經遞質的釋出量。

 Both amphetamine and (-)-PPAP promote the release of monoamines, 

 however while amphetamine causes neurons to dump neurotransmitter stores into the synapse regardless of external input,(-)-PPAP does not influence the pattern of neurotransmitter release and instead releases a larger amount of neurotransmitters than normal.[5]

苯丙氨基戊烷及安非他命皆會促進單胺類的釋放。然而不論有無外界刺激,安非他命都會使神經元將庫存神經傳遞物質運往[[突觸]];苯丙氨基戊烷則是在不改變神經遞質釋放模式的情況下,釋放出比正常量更多的神經傳遞物質.<ref>{{cite journal | url=http://www.sciencedirect.com/science/article/pii/0024320596000148 | title=(−)Deprenyl and (−)1-phenyl-2-propylaminopentane, [(−) PPAP] act primarily as potent stimulants of action potential — transmitter release coupling in the catecholaminergic neurons |author1=Joseph Knoll |author2=Ildikó Miklya |author3=Berta Knoll |author4=Raissa Markó |author5=Károly Kelemen | journal=Life Sciences | date=February 1996 | volume=58 | issue=10 | pages=817–827 | doi=10.1016/0024-3205(96)00014-8 | pmid=8602114}}</ref>

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(-)-PPAP has no monoamine oxidase inhibitory activity.[6]

苯丙胺基戊烷不抑制單胺氧化酶<ref>{{cite journal | url=http://onlinelibrary.wiley.com/doi/10.1002/cbf.1183/abstract | title=Acute and delayed effect of (−) deprenyl and (−) 1-phenyl-2-propylaminopentane (PPAP) on the serotonin content of peritoneal cells (white blood cells and mast cells) |author1=G. Csaba |author2=P. Kovács |author3=Éva Pállinger | journal=Cell Biochemistry and Function | date=January–February 2006 | volume=24 | issue=1 | pages=49–53 | doi=10.1002/cbf.1183 | pmid=15584092}}</ref>

2016/9/30 整合至維基百科上