’’’雷尼替丁’’’（{{lang|en|Ranitidine}}），常用商品名’’’Zantac’’’。為降低[[胃酸]]分泌的藥物<ref name=AHFS2015/>，通常用於治療[[胃及十二指肠潰瘍]]及[[胃食管反流病]]<ref name=AHFS2015/> 。此外，該藥或許還能改善[[荨麻疹]]的症狀<ref>{{cite journal|last1=Fedorowicz|first1=Z|last2=van Zuuren|first2=EJ|last3=Hu|first3=N|title=Histamine H2-receptor antagonists for urticaria.|journal=The Cochrane database of systematic reviews|date=14 March 2012|volume=3|pages=CD008596|pmid=22419335}}</ref>。本品可經口服、{{tsl|en|intramuscular|肌肉注射}}，或[[靜脈注射]]給藥<ref name=AHFS2015/> 。
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注射劑常見副作用包含[[頭痛]]以及灼熱感<!-- <ref name=AHFS2015/> -->，嚴重副作用則包含肝臟疾病、[[心跳过缓]]、[[肺炎]]，且可能使[[胃癌]]更不易發現<ref name=AHFS2015/>。本品也可能提升[[偽膜性結腸炎]]的風險<ref>{{cite journal|last1=Tleyjeh|first1=IM|last2=Abdulhak|first2=AB|last3=Riaz|first3=M|last4=Garbati|first4=MA|last5=Al-Tannir|first5=M|last6=Alasmari|first6=FA|last7=Alghamdi|first7=M|last8=Khan|first8=AR|last9=Erwin|first9=PJ|last10=Sutton|first10=AJ|last11=Baddour|first11=LM|title=The association between histamine 2 receptor antagonist use and Clostridium difficile infection: a systematic review and meta-analysis.|journal=PloS one|date=2013|volume=8|issue=3|pages=e56498|pmid=23469173}}</ref>。[[妊娠]]期間給藥目前顯示安全<!-- <ref name=AHFS2015/> -->。本品屬於[[組織胺]][[H2受体阻抗剂|H<sub>2</sub>受体阻抗剂]]，可降低胃酸的分泌<ref name=AHFS2015>{{cite web|title=Ranitidine|url=http://www.drugs.com/monograph/ranitidine-hydrochloride.html|publisher=The American Society of Health-System Pharmacists|accessdate=Dec 1, 2015}}</ref>。
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雷尼替丁最早於1976年由葛蘭素製藥（Glaxo Pharmaceuticals）發現，現屬於[[葛蘭素史克]]的一部分<ref>{{cite book|last1=Fischer|first1=Janos|title=Analogue-based Drug Discovery II|date=2010|publisher=John Wiley & Sons|page=4|isbn=9783527632121|url=https://books.google.ca/books?id=h2Kd8ci4Ln8C&pg=PA4}}</ref><ref>{{cite book|last1=Hara|first1=Takuji|title=Innovation in the pharmaceutical industry the process of drug discovery and development|date=2003|publisher=Edward Elgar|location=Cheltenham, U.K.|isbn=9781843765660|page=94|url=https://books.google.ca/books?id=aYP-AQAAQBAJ&pg=PA94}}</ref>。本品列名於[[世界卫生组织基本药物标准清单]]之中，為基礎公衛體系必備藥物之一<ref>{{cite web|title=WHO Model List of EssentialMedicines|url=http://apps.who.int/iris/bitstream/10665/93142/1/EML_18_eng.pdf?ua=1|work=World Health Organization|accessdate=22 April 2014|date=October 2013}}</ref> xxxx為學名藥。<ref name=AHFS2015/>。本品批發價每顆約位於0.01至0.05美金之間<ref>{{cite web|title=Ranitidine|url=http://erc.msh.org/dmpguide/resultsdetail.cfm?language=english&code=RAN150T&s_year=2014&year=2014&str=150%20mg&desc=Ranitidine&pack=new&frm=TAB-CAP&rte=PO&class_code2=17%2E1%2E&supplement=&class_name=%2817%2E1%2E%29Antiulcer%20medicines%3Cbr%3E|website=International Drug Price Indicator Guide|accessdate=1 December 2015}}</ref>。美國境內一劑約需0.05美金<ref name=AHFS2015/>。