英文版列言：https://en.wikipedia.org/wiki/Wikipedia:WikiProject_Medicine/Translation_task_force/RTT/Simple_Calcium_channel_blocker_toxicity
Calcium channel blocker toxicity, calcium channel blocker poisoning or calcium channel blocker overdose is the taking of too much of the medications known as calcium channel blockers either by accident or on purpose.[1] This often causes a slow heart rateand low blood pressure.[2] This can progress to the heart stopping altogether. Other symptoms may include nausea, vomiting, sleepiness, and shortness of breath. Symptoms usually occur in the first six hours but with some forms of the medication may not start until 24 hours.[3]
’’’钙离子通道阻滞剂中毒’’’（{{lang|en|Calcium channel blocker toxicity, calcium channel blocker poisoning}}）是指因服用過量[[钙离子通道阻滞剂]]類的藥物而造成的疾病[1]。會造成[[心跳过缓]]及[[低血壓]][2]，且可能會進展為[[心收縮不全]]。其他症狀包括[[噁心]]、[[嘔吐]]、嗜睡、及[[呼吸困难]]。一般症狀會在攝取藥物後的頭六小時出現，不過有些藥物要到二十四小時後才會出現[3]。
There are a number of treatments that may be useful. These include efforts to reduceabsorption of the drug including: activated charcoal taken by mouth if given shortly after the ingestion or whole bowel irrigation if an extended release formula was taken. Efforts to cause vomiting are not recommended.[2] Medications to treat the toxic effects include: intravenous fluids, calcium gluconate, glucagon, high dose insulin, vasopressors and lipid emulsion.[2][3] Extracorporeal membrane oxygenation may also be an option.[2]
有幾項可能有效的治療方法，其中包括試著減少藥物的{{le|吸收 (藥理學)|Absorption (pharmacokinetics)|吸收}}：在吃下鈣離子阻斷劑後立刻口服[[活性炭]]，或是當病患服用{{le|緩釋技術|Time release technology|緩釋型}}鈣離子阻斷劑後進行{{le|全腸道浣腸|Whole bowel irrigation}}，但不建議催吐[2]。針對鈣離子阻斷劑毒性作用的藥物治療包括：靜脈點滴、[[葡萄糖酸鈣]]、[[升糖素]]、高劑量的[[胰島素]]、[[血管收縮劑]]和{{le|脂質乳劑|Lipid emulsion}}[2][3]。[[體外膜氧合]]（葉克膜）也可能是可行的選項[2]。
Greater than ten thousand cases of calcium channel blocker toxicity were reported in the United States in 2010. Along with beta blockers and digoxin calcium channel blockers have one of the highest rates of death in overdose.[3] These medications first became available in the 1970s and 1980s. It is one of the few medications in which one pill can result in the death of a child.[3]
在2010年的美國，有通報的鈣離子通道阻斷劑中毒超過一萬件。在藥物劑量過多的案例中，鈣離子通道阻斷劑、[[Β受体阻断药|貝他阻斷劑]]和[[地高辛]]，都是死亡率最高的藥物之一[3]。這些藥物從1970~1980年代開始被使用。鈣離子通道阻斷劑是少數一個藥錠就能造成孩童死亡的藥物之一[3]。