霍亂疫苗 (Cholera vaccine)

審定版:https://en.wikipedia.org/wiki/Wikipedia:WikiProject_Medicine/Translation_task_force/RTT/Simple_cholera_vaccine

中文:沒有中文條目

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Cholera vaccines are vaccines that are effective in preventing cholera.[1] They are about 85% effective during the first six months and 50–60% effective during the first year.[1][2][3]  The effectiveness decreases to less than 50% after two years. When a  significant portion of the population is immunized benefits from herd immunity may occur among those not immunized. The World Health Organization  recommends their use in combination with other measures among those at  high risk. Two doses or three doses of the oral form are typically  recommended.[1] An injectable forms is available in some areas of the world but its availability is less.[2][1]

<!-- 定義與藥物使用 -->

’’’霍亂疫苗’’’({{lang-en|cholera vaccine}})是一種可有效預防[[霍亂]]的[[疫苗]][1]。約85%施打過疫苗的人在施打後6個月仍有效力,50-60%的人在施打後一年仍有效力[1,2,3]。施打後兩年,仍受疫苗保護的人數會降低到50%以下。當社群裡有足夠比例的人受到疫苗保護,就可能產生[[群體免疫]]現象,因而讓不受保護的人免於罹患霍亂。[[世界衛生組織]]建議感染霍亂風險較高的人在疫苗接種外也應該併用其他防治方式。目前建議口服的霍亂疫苗需要重覆服用二到三次[1],部分國家也備有針劑式霍亂疫苗,但針劑較不易取得[2][1]。

Both of the available types of oral vaccine are generally safe. Mild abdominal pain or diarrhea may occur. They are safe in pregnancy and in those with poor immune function.  They are licensed for use in more than 60 countries. It use in  countries where the disease is common appears to be cost effective.[1]

<!-- 安全性 -->

兩種口服藥劑通常都是安全的,但可能會有輕微腹痛或腹瀉的副作用。對[[妊娠|孕婦]]和[[免疫缺陷|免疫功能較差]]者,兩種藥劑也都是安全的。霍亂疫苗在60多個國家取得藥物許可證。在霍亂盛行的國家使用疫苗防治,是符合成本效益的[1]。

The first vaccines used against cholera were developed in the late  1800s. They were the first widely used vaccine that was made in a  laboratory.[4] Oral vaccines were first introduce in the 1990s.[1] It is on the World Health Organization’s List of Essential Medicines, the most important medication needed in a basic health system.[5] The cost to immunize against cholera is between 0.1 and 4.0 USD.[6]

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第一支霍亂疫苗開發於1800年代後期,這是第一個由實驗室製造並大規模施打的疫苗[4]。1990年代,口服疫苗首次引入[1]。在[[世界衛生組織基本藥物標準清單]]上,霍亂疫苗是{{link-en|衛生系統|health system}}中最重要的必需藥品[5]。霍亂防疫的成本在美金1角到4元之間[6]。