英文引言：https://en.wikipedia.org/wiki/Wikipedia:WikiProject_Medicine/Translation_task_force/RTT/Simple_PAD：
Peripheral artery disease (PAD), also known as peripheral vascular disease (PVD) peripheral artery occlusive disease, andperipheral obliterative arteriopathy, is narrowing of arteries(动脉) other than those that supply the heart or brain.[1] Most commonly the legs are affected.[2] The classic symptoms are leg pain when walking which resolves with rest.[3] Other symptoms including: skin ulcers, bluish skin, cold skin, or poor nail and hair growth may occur in the affected leg.[4] Complications may include an infection or tissue death(坏疽) which may requires amputation(截肢), coronary artery disease(冠狀動脈疾病), or stroke(中風).[2] In up to half of people there are no symptoms.[3]
’’’周邊動脈疾病’’’（{{lang|en|Peripheral artery disease, PAD}}），可以稱為’’’周邊血管疾病’’’（Peripheral vascular disease, PVD）、’’’周邊動脈阻塞性疾病’’’（Peripheral artery occlusive disease, PAOD），或是’’’周邊閉塞性動脈病變’’’（Peripheral obliterative arteriopathy, POA），是一種供應大腦和心臟以外之[[動脈]]的窄化現象[1]。多數的情況下，患者的雙腿會被影響[2]。典型的症狀是{{le|跛行|Claudication|走路時腳痛}}，但這種症狀在休息時便可改善。 其他症狀包括：{{le|動脈供血不足性潰瘍|Arterial insufficiency ulcer|皮膚潰瘍}}、皮膚偏藍、冰冷，或是患肢的指甲和毛髮生長較差[4]。併發症可能包括感染或[[壞疽]]，可能會導致[[截肢]]、[[冠狀動脈疾病]]或[[中風]][2]。不過有將近一半的病患是沒有症狀的。
The main risk factor is cigarette smoking(吸菸).[2] Other risk factors include diabetes(糖尿病), high blood pressure(高血壓), and high blood cholesterol.[5] The underlying mechanism is usually atherosclerosis(动脉粥样硬化) which if it breaks open may result in complete closure of the artery.[6] Other causes include artery spasm.[1] PAD is typically diagnosed by finding an ankle-brachial index(踝肱指数) (ABI) less than 0.90, which is the systolic blood pressure(血壓) at the ankle divided by the systolic blood pressure of the arm.[7] Angiography(血管攝影) is a more accurate diagnostic test but carries some risks.[7]
周邊動脈阻塞最主要的危險因子是[[吸菸]][2]。其他危險因子包括[[糖尿病]]、[[高血壓]] 和{{le|血膽固醇過高|Hypercholesterolemia|高膽固醇}}[5]。其潛在的致病機轉通常是[[動脈粥樣硬化]]，如果硬化的斑塊脫落將會導致動脈的完全阻塞[6]。其他原因包含[[動脈痙攣]][1]。周邊動脈阻塞通常藉由發現[[踝肱指數]]（Ankle-brachial index, ABI）低於0.90而確診，踝肱指數的公式是腳踝的收縮壓除以手臂的收縮壓[7]。[[血管攝影]]是更準確的診斷方法，不過它具有一定的風險[7]。
It is unclear if screening for disease is useful as it has not been properly studied.[8][9] In those with PAD stopping smoking and supervised exercise therapy improves outcomes.[10][11] Medications, including statins(羟甲基戊二酸单酰辅酶A还原酶抑制剂), ACE inhibitors(血管紧张肽I转化酶抑制剂), and cilostazol also may help.[11][12] Aspirin(阿司匹林) does not appear to help those with mild disease but is usually recommended in those with more significant disease.[13][14] Warfarin(华法林) is not typically of benefit.[15]Procedures used to treat the disease include: bypass grafting(冠状动脉旁路移植), angioplasty(血管再成形術), and atherectomy.[16]
目前篩檢的效果仍待進一步研究[8][9]。對於周邊動脈阻塞的病患，戒菸和{{le|運動療法|Exercise_therapy}}能夠改善[10][11]。 藥物治療包括[[羟甲基戊二酸单酰辅酶A还原酶抑制剂|HMG-CoA還原酶抑制劑]]（Statin） 、[[血管紧张肽I转化酶抑制剂|ACE抑制劑]]和{{le|cilostazol|西洛他唑}} 都會有幫助[11][12]。[[阿司匹林]]對於輕症患者沒有顯著幫助，但通常會建議較嚴重的患者使用[13][14]。[[华法林]]並沒有特別效益[15]。一些用來治療周邊動脈阻塞的手術包括[[冠状动脉旁路移植]]、[[血管再成形術]] 和 {{le|旋切術|atherectomy}}[16]。
In 2010 about 202 million people had PAD worldwide.[5] In the developed world it affects about 5.3% of 45 to 50 years olds and 18.6% of 85 to 90 year olds.[5] In the developing world it affects 4.6% of people between the ages of 45 to 50 and 15% of people between the ages of 85 to 90.[5] In the developed world PAD is equally common among men and women while in the developing world women are more commonly affected.[5] In 2013 PAD resulted in about 41,000 deaths up from 16,000 deaths in 1990.[17]
於2010年，全世界有將近2.02億人有周邊動脈阻塞的疾病[5]。 在已開發國家，周邊動脈阻塞在45至50歲的民眾中佔了5.3%，85至90歲中佔了18.6% [5]；而在開發中國家，45至50歲的民眾中佔了4.6%，85至90歲中佔了15% [5]。在已開發國家，男女罹病的比例相當；但在開發中國家則是女性較容易罹病[5]。 在1990年，周邊動脈阻塞造成近16,000的死亡；在2013年，周邊動脈阻塞造成的死亡數更高達近41,000人[17]。
2016/4/10 已更新至中文維基百科