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Clindamycin is an antibiotic(抗细菌药) useful for the treatment of a number of bacterial infections(病原细菌).[1] This includes middle ear infections(中耳炎), bone or joint infections(化膿性關節炎), pelvic inflammatory disease(骨盆腔發炎), strep throat(链球菌性咽炎), pneumonia(肺炎), and endocarditis among others.[1] It can be useful against some cases of methicillin-resistant Staphylococcus aureus(耐甲氧西林金黄色葡萄球菌) (MRSA).[2]It may also be used for acne(粉刺) and in addition to quinine(奎寧) for malaria(疟疾). It is available by mouth, intravenously(靜脈注射), and as a cream to be applied to the skin or in the vagina.[3][1]
克林黴素是用於治療多種[[細菌感染]]的[[抗生素]][1] 。其中包括[[中耳炎]]、骨髓炎或[[化膿性關節炎]]、[[盆腔炎]]、[[鏈球菌性咽炎]]、[[肺炎]]以及[[心內膜炎]]等細菌感染性疾病[1]。克林黴素可用於治療[[耐甲氧西林金黄色葡萄球菌(MRSA)]]引起的感染[2]，也可用於治療[[粉刺]]，當與[[奎寧]]合併使用時可用於治療[[瘧疾]]。克林黴素可通過口服、[[靜脈注射]]使用，也可以製成乳膏塗抹於皮膚或陰道[3][1]。
Common side effects include nausea, diarrhea, rash, and pain at the site of injection.[1]It increases the risk of Clostridium difficilecolitis(偽膜性結腸炎) by about fourfold.[4]Other antibiotics may be recommended instead due to this reason.[1] It appears to be generally safe in pregnancy. It is of the lincosamide class(林可酰胺类抗生素) and works by blocks the making of protein.[1]
常見的副作用包含噁心、腹瀉、皮疹和注射部位疼痛 [1]。克林黴素也增加了[[偽膜性結腸癌]]的風險達四倍之多[4]。若有這方面的考量可改用其他抗生素[1]。克林黴素用於孕婦是安全的。克林黴素屬於[[林可酰胺类抗生素]]，作用機轉為抑制細菌合成蛋白質[1]。
Clindamycin was first made in 1967.[5] It is on the World Health Organization’s List of Essential Medicines(世界卫生组织基本药物标准清单), the most important medication needed in a basic health system.[6] It is available as a generic medication(通用名药物) and is not very expensive.[7] The wholesale cost is about 0.06 to 0.12 USD per pill.[8] In the United States it costs about 2.70 USD a dose.[1]
克林黴素首次合成於1967年[5] 。它被列入[[世界卫生组织基本药物标准清单]]中，是基層[[衛生系統]]需要的最重要的藥物之一[6]。它也被製成許多種廉價的[[仿製藥]]。其批發價約為每片0.06至0.12美元[8] ，在美國其零售價約為每劑量2.7美元[1]。