醫週譯:Lymphoma/淋巴瘤

編輯歷史

時間 作者 版本
2017-07-17 16:39 – 16:39 (unknown) r0 – r1
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+ 醫週譯:Lymphoma/淋巴瘤
+ <!-- Definition and Symptoms -->
+ Lymphoma is a group of blood cell tumors that develop fromlymphocytes.[1] It is sometimes used to refer to just the cancerous ones rather than all tumors.[1] Symptoms may include: enlarged lymph nodes that are not generally painful, fevers, sweats, itchiness, weight loss and feeling tired among others.[2][3] The sweats are most common at night.[2][3]
+ <!-- 定義與病徵 -->
+ '''淋巴瘤(Lymphoma)'''又稱'''淋巴癌''',是由[[淋巴細胞]]病變造成的{{link-en|血液細胞瘤|blood cell tumors}}[1]。有時候這個詞彙被用來單指[[癌症]]、而不包括良性的腫瘤。症狀包括[[淋巴結|淋巴結腫大]] (通常為無痛性)、[[發燒]]、[[盜汗]]、[[皮膚癢]]、體重減輕,以及疲倦感[2][3]。而盜汗則通常在夜晚發生[2][3]。
+ *[1]<ref name=D2000>{{cite book|last1=Taylor|first1=Elizabeth J.|title=Dorland's Illustrated medical dictionary.|date=2000|publisher=Saunders|location=Philadelphia|ISBN=0721662544|page=1038|edition=29th ed.}}</ref>
+ *[2]<ref name=HL2014>{{cite web|title=General Information About Adult Hodgkin Lymphoma|url=http://www.cancer.gov/cancertopics/pdq/treatment/adulthodgkins/Patient/page1/AllPages|website=National Cancer Institute|accessdate=20 June 2014|date=2014-04-23}}</ref>[3]<ref name=NHL2014>{{cite web|title=General Information About Adult Non-Hodgkin Lymphoma|url=http://www.cancer.gov/cancertopics/pdq/treatment/adult-non-hodgkins/Patient/page1/AllPages|website=National Cancer Institute|accessdate=20 June 2014|date=2014-04-25}}</ref>
+ *合併一些條目中原本有的資料
+
+ <!-- Classification -->
+ There are two main types: Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL),[4] with two others, multiple myeloma andimmunoproliferative diseases, also include by the World Health Organization within the category.[5] Non-Hodgkin lymphoma makes up about 90% of cases and includes a large number of sub-types.[6][4] Lymphomas are part of the broader group of neoplasmscalled tumors of the hematopoietic and lymphoid tissues.[7]
+
+ <!-- 分類 -->
+ 淋巴瘤主要分為兩大類:[[何杰金氏淋巴瘤]]({{lang-en|Hodgkin lymphoma, HL}})和[[非何杰金氏淋巴瘤]]({{lang-en|non-Hodgkin lymphoma, NHL}})[4],而其他包含在[[世界衛生組織]]分類中的尚有[[多發性骨髓瘤]]及{{link-en|淋巴增生性疾病|Lymphoproliferative_disorders}}[5]。非何杰金氏淋巴瘤佔所有淋巴瘤的90%,其中包含各種次分類[4][6]。淋巴瘤為{{link-en|造血淋巴組織腫瘤|Tumors of the hematopoietic and lymphoid tissues}}的一部分[7]。
+ *[4]<ref name=Society2013>{{cite book|title=The Lymphoma Guide Information for Patients and Caregivers|date=2013|publisher=Leukemia and Lymphoma Society|url=http://www.lls.org/content/nationalcontent/resourcecenter/freeeducationmaterials/lymphoma/pdf/lymphomaguide.pdf|accessdate=20 June 2014}}</ref>
+ *[5]<ref name=WCR2014>{{cite book|title=World Cancer Report 2014.|date=2014|publisher=World Health Organization|isbn=9283204298|pages=Chapter 5.13}}</ref>
+ *[6]<ref>{{cite web|title=Lymphoma|url=http://www.cancer.gov/dictionary?cdrid=45368|website=NCI|accessdate=13 June 2014}}</ref>
+ *[7]<ref>{{cite journal|last1=Vardiman|first1=JW|last2=Thiele|first2=J|last3=Arber|first3=DA|last4=Brunning|first4=RD|last5=Borowitz|first5=MJ|last6=Porwit|first6=A|last7=Harris|first7=NL|last8=Le Beau|first8=MM|last9=Hellström-Lindberg|first9=E|last10=Tefferi|first10=A|last11=Bloomfield|first11=CD|title=The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes.|journal=Blood|date=Jul 30, 2009|volume=114|issue=5|pages=937-51|pmid=19357394}}</ref>
+
+ <!-- Cause and Diagnosis -->
+ Risk factors for HL include: infection with Epstein-Barr virus and having other in the family with the disease.[2] Risk factors for NHL include: autoimmune diseases, HIV/AIDS, infection with human T-lymphotropic virus, eating a large amount of meat and fat, as well asimmunosuppressant medications and some pesticides.[3] They are usually diagnosed by blood, urine, or bone marrow testing.[3] A biopsy of a lymph node may also be useful.[2][3] Medical imaging than may be done to determine if and where the cancer has spread.[2][3] This spread can occur to many other organs including: lungs, liver, and brain.[2][3]
+
+ <!-- 病因與診斷 -->
+ 何杰金氏淋巴瘤的風險因子包含[[EB病毒]]和其他同病毒科[2]。非何杰金氏淋巴瘤的風險因子則包含[[自體免疫疾病]]、[[愛滋病|人類免疫缺乏病毒或愛滋病]]、{{link-en|人類T淋巴細胞病毒|Human T-lymphotropic virus}}感染、攝取過量肉類及脂肪、使用[[免疫抑制劑]]、及部分[[農藥|殺蟲劑]]。通常藉由血液、尿液、{{link-en|骨髓檢查|Bone marrow examination}}診斷淋巴癌[3],而淋巴結[[活體組織切片|切片]]可能有助於診斷[2][3]。[[醫學影像]]可用於淋巴癌細胞是否轉移[2][3],而可發生轉移處有肺、肝、腦等[2][3]。
+ *[2]<ref name=HL2014 />
+ *[3]<ref name=NHL2014 />
+
+ <!-- Treatment and Prognosis -->
+ Treatment may involved some combination of chemotherapy, radiation therapy, targeted therapy and surgery.[2][3]In NHL the blood may become so thick with protein that a procedure called plasmapheresis is needed.[3] Watchful waiting may be appropriate for certain types.[3] Some types are curable.[4] The overall five-year survival rate in the United States for HL is 85%[8] while that for NHL is 69%.[9]
+
+ <!-- 治療與預後 -->
+ 治療淋巴瘤可能會合併[[化學治療]]、[[放射線治療]]、[[標靶治療]]及[[手術]]等多種方式[2][3]。非何杰金氏淋巴瘤患者的血液可能因[[蛋白質]]成分增多而較濃稠,需要接受{{link-en|血漿置換|Plasmapheresis}}的治療[3]。某些型態的淋巴瘤可能必須採用所謂「{{link-en|觀察等待|
+ Watchful waiting}}」的策略[3],而某些型態則可治癒[4]。在美國,何杰金氏淋巴瘤的{{link-en|五年整體存活率|Five-year survival rate}}約85%[8],而非何杰金氏淋巴瘤則僅69%[9]。
+
+ <!-- Epidemiology --> Lymphomas developed in 566,000 people in 2012 and caused 305,000 deaths.[5] They make up 3-4% of all cancers, making them as a group the 7th most common form.[10][5] In children they are the third most common cancer.[11] They occur more often in the developed worldthan the developing world.[5]
+
+ <!-- 流行病學 -->
+ 在2012年,約有566,000人罹患淋巴瘤,並造成305,000死亡[5],佔所有癌症的3至4%,為第七常見[5][10],而在兒童則為第三常見[11]。相對於[[開發中國家]],淋巴瘤通常多發生在[[已開發國家]][5]。
+
+ *[2]<ref name=HL2014 />
+ *[3]<ref name=HL2014 />
+ *[4]<ref name=Society2013 />
+ *[5]<ref name=WCR2014 />
+ *[8]<ref name="seer">{{cite web|url=http://seer.cancer.gov/statfacts/html/hodg.html |title=Hodgkin Lymphoma—SEER Stat Fact Sheets |publisher=Seer.cancer.gov |accessdate=2012-08-26}}</ref>
+ *[9]<ref>{{cite web|title=SEER Stat Fact Sheets: Non-Hodgkin Lymphoma|url=http://seer.cancer.gov/statfacts/html/nhl.html|website=NCI|accessdate=18 June 2014}}</ref>
+ *[10]<ref name=Rob2013>{{cite book|last1=Marcus|first1=Robert|title=Lymphoma : pathology, diagnosis and treatment|date=2013|isbn=9781107010598|page=1|edition=Second edition.|url=http://books.google.ca/books?id=SX0LAgAAQBAJ&lpg=PP1}}</ref>
+ *[11]<ref>{{cite book|last1=Tepper|first1=John E. Niederhuber, James O. Armitage, James H. Doroshow, Michael B. Kastan, Joel E.|title=Abeloff's clinical oncology|date=2014|isbn=1455728659|page=Chapter 97|edition=Fifth edition.|chapter=Childhood lymphoma}}</ref>
+
+ 2014-12-08 已經完成與中文維基百科「淋巴癌」的引言頁面整合
+ 回到工作入口頁